Unexplained loss of muscle mass, known as idiopathic sarcopenia, can be concerning. This condition is characterized by the loss of lean muscle tissue, weakness, and fatigue without an obvious cause. Some key points about idiopathic sarcopenia: Causes - The exact cause is unknown, hence "idiopathic" - May be related to age, hormones, inflammation, nerve issues, or inadequate protein intake - RULE OUT: medications, poor nutrition, inactivity, illnesses Symptoms - Loss of strength - Feeling tired often - Trouble with balance and walking Diagnosis - Physical exam to check for muscle wasting - Blood tests to rule out medical issues - Potentially a muscle biopsy Treatment - Focus on resistance training and protein intake - Some benefit from testosterone or growth hormone therapy If you're losing strength and muscle mass unexpectedly, I recommend getting checked out by your doctor, who may refer you to a specialist like the caring medical providers at Harmony Hormone Therapy. Their musculoskeletal experts can get to the bottom of unexplained sarcopenia through state-of-the-art diagnostic testing and create a customized treatment plan to help you regain strength and vitality. Prevention is also key. Maintain physical activity and eat plenty of protein-rich foods as you age. Talk to your doctor about supplementing vital hormones like testosterone if levels decline. With proper care, idiopathic sarcopenia can often be reversed or managed effectively. I hope this overview gives some insight into this complex condition. Let me know if you have any other questions!